The composition of prepared PHT-loaded NPs.
| NP# | Chitosan (mg) | Lecithin (mg) | L/CS ratio | Phenytoin (mg) | Surfactant | Method of adding PHT & triacetin to organic phase |
|---|---|---|---|---|---|---|
| L5Ci+ | 0.1 | 5 | 50 | 1.2 | Tween 80 | Phenytoin was added as a solute in triacetin |
| L5Cii+ | 0.25 | 20 | ||||
| L5Ciii+ | 20 | 4 | ||||
| L10Ci+ | 1.25 | 1.0 | 8 | |||
| L10Cii+ | 5 | 2 | ||||
| L10Ciii+ | 20 | 2.5 | ||||
| L25Ci+ | 0.5 | 25 | 50 | |||
| L25Cii+ | 1.25 | 20 | ||||
| L25Ciii+ | 20 | 1.25 | ||||
| L35Ciii+ | 35 | 1.25 | ||||
| L50Ciii+ | 50 | 1.25 | ||||
| L25CiiiT20+ | 25 | 1.25 | Tween 20 | |||
| L25CiiiPX188 | 1.25 | Poloxamer 188 | ||||
| L25CiiiP3+ | 1.25 | 0.3 | Tween 80 | |||
| L25CiiiP6+ | 1.25 | 0.6 | ||||
| LCiiiO− | 1.25 | 1.2 | Triacetin was not added | |||
| L25CiiiOs | 1.25 | Phenytoin and triacetin were added separately |