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Fig. 7. Plots of uptake amount of P (5 and 10 μg mL−1) and P2D (0.5 and 1 μg mL−1) into MDA-MB-231 spheroids by flow cytometry method, where the blank- and Hoechst-stained spheroids were used as the unstained and stained control, respectively. The uptake percentage was labeled on every section (C, M and R represent the core, middle and rim of the spheroid, respectively).