Fig. 8. (A) Results of cytotoxicity of all the formulations (P2D, 2D, PD, Dox, PC and Conf concentration: 0.058, 0.117, 0.234, 0.468, 0.937, 1.875 and 3.75 μg mL⁻¹) on the MDA-MB-231 cell line using the MTT method. (B) Results of Dox and Conf nephrotoxicity (on HEK-293 cell line) using the MTT method (Dox and Conf concentration: 0.019, 0.39, 0.781, 1.562, and 3.125 μg mL⁻¹). (C) Blank micelles (P concentration: 31.25, 62.5, 125, and 250 μg mL⁻¹) cytotoxicity on MDA-MB-231 cell line using the MTT method (all data was analyzed statistically using the Prism software, n = 3, and the differences between treatments was statistically significant, p < 0.0001).