Table I.
Baseline characteristics stratified by postoperative VTE
| VTE | ||||
|---|---|---|---|---|
| Characteristic | No (n = 1400; 96.6%) | Yes (n = 49; 3.4%) | Total (N = 1449; 100%) | P value |
| Age | 68 ± 13 | 65 ± 14 | 68 ± 13 | .09 |
| Male sex | 66 | 68 | 66 | .88 |
| BMI, kg/m2 | .49 | |||
| <19 | 6 | 6 | 6 | |
| 19–30 | 70 | 77 | 70 | |
| >30 | 24 | 17 | 24 | |
| Length of stay, days | 7 (4–12) | 16 (10–26) | 7 (4–12) | <.01 |
| Nonelective admission | 45 | 60 | 46 | .04 |
| CKD-5 | 14 | 37 | 15 | <.01 |
| CAD | 34 | 24 | 34 | .17 |
| DM | 31 | 27 | 31 | .53 |
| COPD | 19 | 20 | 19 | .99 |
| Smoking history | 30 | 24 | 30 | .43 |
| Impaired mobility | 2 | 8 | 2 | .03 |
| Malignancy | 0.6 | 2.0 | 0.7 | .29 |
| Hypercoagulable disorder | 11 | 16 | 11 | .16 |
| Varicose veins | 3.3 | 2.0 | 3.2 | .99 |
| Inflammatory bowel disease | 0.9 | 2.0 | 0.9 | .39 |
| Central venous catheter placed during admission | 7 | 37 | 8 | <.01 |
| Sepsis (≤1 month) | 6 | 29 | 7 | <.01 |
| Acute MI (≤1 month) | 5 | 12 | 5 | .03 |
| Acute stroke (≤1 month) | 5 | 10 | 6 | .22 |
| Pneumonia or severe lung disease (≤1 month) | 9 | 27 | 9 | <.01 |
| Prior VTE | 4 | 26 | 4 | <.01 |
| Preoperative creatinine, mg/dL | 1.0 (0.8–1.3) | 0.9 (0.7–1.4) | 1.0 (0.8–1.3) | .39 |
| Caprini score | 5 (4–7) | 8 (6–10) | 5 (5–7) | <.01 |
| Caprini score ≥7 | 27 | 65 | 29 | <.01 |
| Interval to chemoprophylaxis,a days | .07 | |||
| <3 | 40 | 35 | 39 | |
| >3 | 11 | 22 | 12 | |
| None | 49 | 43 | 49 | |
| Interval to chemoprophylaxis or anticoagulation, days | .20 | |||
| <2 | 33 | 20 | 32 | |
| 2–4 | 23 | 26 | 23 | |
| >4 or nonea | 45 | 53 | 45 | |
| Interval to chemoprophylaxis, anticoagulation, antiplatelet, days | <.01 | |||
| <2 | 68 | 45 | 67 | |
| 2–4 | 15 | 22 | 16 | |
| >4 or nonea | 17 | 33 | 17 | |
| ≥2 pRBCs transfused postoperatively (days 1–7) | 14 | 29 | 14 | <.01 |
| Return to OR for bleeding (30 days) | 0.8 | 4.1 | 0.9 | .07 |
| Return to OR bleeding or ≥2 pRBCs transfused postoperatively (days 1–7) | 14 | 31 | 15 | <.01 |
| Nonhome discharge | 29 | 49 | 30 | <.01 |
| Mortality at 30 days | 3.5 | 10.4 | 4.7 | .05 |
| Mortality at 90 days | 4.8 | 20.8 | 5.3 | <.01 |
BMI, Body mass index; CAD, coronary artery disease; CKD-5, chronic kidney disease stage 5; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; MI, myocardial infarction; OR, operating room; pRBCs, packed red blood cells; VTE, venous thromboembolism.
Data presented as mean ± standard deviation, percentages, or median (interquartile range).
a
Including patients who started anticoagulation or antiplatelet therapy after a VTE diagnosis.