Table 3.

Comparison of PWE with/without seizure increase in epilepsy-related condition

Variables	PWE without seizure increase (n=1134)	PWE with seizure increase (n=103)	P value
Epilepsy course (month)	101.89±97.77	119.38±101.39	0.095
Seizure type			0.867
Generalised seizures	526 (46.4%)	45 (43.7%)
Partial seizures	568 (50.1%)	54 (52.4%)
Unidentified	40 (3.5%)	4 (3.9%)
Seizure control before the COVID-19 outbreak			0.000***
No seizure	476 (42.0%)	6 (5.8%)
Seizure reduction > 90%	289 (25.5%)	20 (19.4%)
Seizure reduction ≥50%	140 (12.3%)	26 (25.2%)
Seizure reduction < 50%	104 (9.2%)	15 (14.6%)
No reduction	125 (11.0%)	36 (35.0%)
Number of doses missing before the COVID-19 outbreak			0.184
0	904 (79.7%)	79 (76.7%)
1-2 doses/week	200 (17.6%)	18 (17.5%)
≥3 doses/week	30 (2.6%)	6 (5.8%)
Number of doses missing during the COVID-19 outbreak
1.000
0	904 (79.7%)	83 (80.6%)
1-2 doses/week	191 (16.8%)	17 (16.5%)
≥3 doses/week	39 (3.4%)	3 (2.9%)
Number of AEDs before the COVID-19 outbreak			0.006**
1	584 (51.5%)	38 (36.9%)
2	372 (32.8%)	37 (35.9%)
3	95 (8.4%)	15 (14.6%)
>3	31 (2.7%)	8 (7.8%)
Never took AEDs	33 (2.9%)	4 (3.9%)
Stop medication	19 (1.7%)	1 (1.7%)
Medication alteration during the COVID-19 outbreak			0.000***
None	1077 (95.0%)	86 (83.5%)
Increase	38 (3.4%)	10 (9.7%)
Reduction/withdrawal	19 (1.7%)	7 (6.8%)
Worry about seizure attack during the COVID-19 outbreak			0.000***
None	478 (40.9%)	14 (13.6%)
A little	399 (35.2%)	30 (29.1%)
Medium	72 (6.3%)	8 (7.8%%)
Fairly much	111 (9.8%)	22 (21.4%)
Very much	88 (7.8%)	29 (28.2%)
Worry about the pandemic's impact on seizure control			0.000***
None	606 (53.4%)	30 (29.1%)
A little	321 (28.3%)	32 (31.1%)
Medium	54 (4.8%)	7 (6.8%)
Fairly much	87 (7.7%)	12 (8.2%)
Very much	66 (5.8%)	22 (21.4%)

** P<0.01, *** P<0.001.