Table 3.

Other CODs and prostate-related hazard ratio of patients adjusted for demographic and clinical characteristics.

Variables	Other CODs		Prostate
	sHRa	P value	sHRa	P value
Marital
Married	1.00 (ref.)		1.00 (ref.)
Widowed/divorced	1.40 (1.38 − 1.42)	<0.001	1.20 (1.17 − 1.23)	<0.001
Single	1.35 (1.32 − 1.38)	<0.001	1.12 (1.09 − 1.26)	<0.001
Unknown	1.17 (1.15 − 1.19)	<0.001	0.92 (0.89 − 0.95)	<0.001
Age
< 50	1.00 (ref.)		1.00 (ref.)
50 − 64	1.97 (1.83 − 2.12)	<0.001	1.03 (0.97 − 1.10)	0.357
65 − 74	4.66 (4.34 − 5.00)	<0.001	1.08 (1.01 − 1.15)	0.024
≥75	10.51 (9.78 − 11.29)	<0.001	1.46 (1.37 − 1.56)	<0.001
Race
White	1.00 (ref.)		1.00 (ref.)
Black	1.20 (1.18 − 1.22)	<0.001	1.06 (1.03 − 1.08)	<0.001
Other	0.86 (0.83 − 0.88)	<0.001	0.78 (0.75 − 0.81)	<0.001
Unknown	0.26 (0.24 − 0.28)	<0.001	0.13 (0.11 − 0.15)	<0.001
Year of diagnosis
2000–2005	1.00 (ref.)		1.00 (ref.)
2006–2016	0.71 (0.70 − 0.71)	<0.001	0.67 (0.66 − 0.69)	<0.001
Stage
Local	1.00 (ref.)		1.00 (ref.)
Regional	1.04 (1.01 − 1.06)	0.003	3.79 (3.67 − 3.90)	<0.001
Distant	0.58 (0.56 − 0.59)	<0.001	12.09 (11.80 − 12.39)	<0.001
Unknown	0.93 (0.90 − 0.96)	<0.001	3.05 (2.95 − 3.15)	<0.001
Grading
I	1.00 (ref.)		1.00 (ref.)
II	1.00 (0.97 − 1.04)	0.828	1.79 (1.60 − 2.00)	<0.001
III	1.12 (1.08 − 1.16)	<0.001	5.74 (5.13 − 6.42)	<0.001
IV	1.10 (0.99 − 1.23)	0.082	9.27 (7.94 − 10.82)	<0.001
Unknown	1.03 (0.99 − 1.07)	0.175	6.52 (5.82 − 7.31)	<0.001
Therapy
None	1.00 (ref.)		1.00 (ref.)
RP±RT/CT	0.36 (0.35 − 0.37)	<0.001	0.15 (0.14 − 0.15)	<0.001
RT/CT	0.69 (0.68 − 0.70)	<0.001	0.69 (0.67 − 0.70)	<0.001
Unknown	0.87 (0.83 − 0.91)	<0.001	1.20 (1.13 − 1.28)	<0.001

^aRepresenting multivariable-adjusted competing risks, adjusted for marital, age at diagnosis, race, year of diagnosis, stage, grading, and therapy.