Summary of properties of compounds 18 to 20.
Compound | Condition of synthesis | Yield (%) | Activity | Outcome | Reference |
---|---|---|---|---|---|
18 | 6 h reflux of precursors in EtOH | 60 | Antibacterial/antifungal and DNA cleavage | Cu(ii) complex showed the highest activities but was not compared with curcumin | 41 |
19 | 6 h reflux of precursors in EtOH | 60 | Antibacterial/antifungal and DNA cleavage | Cu(ii) complex was the most potent compound but was not compared with curcumin | 42 |
20 | 6 h reflux of precursors in EtOH | 63 | Antibacterial/antifungal and DNA cleavage | Cu(ii) complex showed the highest activities but was not compared with curcumin | 43 |