Summary of properties of compounds 21 to 23.

Compound	Condition of synthesis	Yield (%)	Activity	Outcome	Reference
21a–f and 22d,f	Heating of precursors in 2-methyl-THF or EtOH under microwave irradiation for 75–105 min at 80–85 °C in presence of MK10 clay and acetic acid	6–24	Anticancer and antioxidant	Enhanced water-solubility, comparable anticancer and lower antioxidant activities to curcumin	44
23a–m	10 h reflux of precursors in EtOH in presence of acetic acid	45–94	Anticancer	23l was the most potent compound but was not compared with curcumin	45