32–35 |
32 and 34: 6–8 h reflux of α,β-unsaturated carbonyl compounds with NH2OH·HCl in EtOH |
42–62 |
Anticancer |
34f and 34g were the most potent anticancer agents |
60
|
33 and 35: 8 h reflux of 32 and 34 with haloalkylamine in dry acetone in presence of K2CO3
|
36a–h |
Reflux of α,β-unsaturated carbonyl compounds with NH2OH·HCl in EtOH |
39–51 |
Anticancer |
36g and 36h were the most potent anticancer agents |
61
|
37a–k |
Stirring of precursors for 5 h at 0–5 °C in dry acetone in presence of K2CO3
|
48.2–76 |
Anti-inflammatory |
37j was the most potent anti-inflammatory agent |
62
|