L9 (34) orthogonal experimental design and the results of LPC-LP preparationsa.
No. | Factors | EE% | |||
---|---|---|---|---|---|
A | B | C | D | ||
1 | 8 : 1 | 34 : 1 | 100 : 1 | 5 | 58.51 |
2 | 8 : 1 | 68 : 1 | 50 : 1 | 10 | 29.00 |
3 | 8 : 1 | 102 : 1 | 20 : 1 | 15 | 13.77 |
4 | 16 : 1 | 34 : 1 | 50 : 1 | 15 | 61.84 |
5 | 16 : 1 | 68 : 1 | 20 : 1 | 5 | 21.15 |
6 | 16 : 1 | 102 : 1 | 100 : 1 | 10 | 83.74 |
7 | 32 : 1 | 34 : 1 | 20 : 1 | 10 | 21.88 |
8 | 32 : 1 | 68 : 1 | 100 : 1 | 15 | 79.27 |
9 | 32 : 1 | 102 : 1 | 50 : 1 | 5 | 38.66 |
K 1 | 33.76 | 47.41 | 73.84 | 39.44 | |
K 2 | 55.58 | 43.14 | 43.17 | 44.87 | |
K 3 | 46.60 | 45.39 | 18.93 | 51.63 | |
R | 21.82 | 4.27 | 54.91 | 12.19 |
A: the ratio of PC to Chol (n/n); B: the ratio of PC to DSPE-mPEG2000 (n/n); C: the ratio of PC to LPC (n/n); D: ultrasonic time, K1, K2 and K3 are the mean response values of corresponding levels. R represents the extreme difference of each factor.