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. 2020 Aug 14;10(50):30025–30034. doi: 10.1039/d0ra05752e

L9 (34) orthogonal experimental design and the results of LPC-LP preparationsa.

No. Factors EE%
A B C D
1 8 : 1 34 : 1 100 : 1 5 58.51
2 8 : 1 68 : 1 50 : 1 10 29.00
3 8 : 1 102 : 1 20 : 1 15 13.77
4 16 : 1 34 : 1 50 : 1 15 61.84
5 16 : 1 68 : 1 20 : 1 5 21.15
6 16 : 1 102 : 1 100 : 1 10 83.74
7 32 : 1 34 : 1 20 : 1 10 21.88
8 32 : 1 68 : 1 100 : 1 15 79.27
9 32 : 1 102 : 1 50 : 1 5 38.66
K 1 33.76 47.41 73.84 39.44
K 2 55.58 43.14 43.17 44.87
K 3 46.60 45.39 18.93 51.63
R 21.82 4.27 54.91 12.19
a

A: the ratio of PC to Chol (n/n); B: the ratio of PC to DSPE-mPEG2000 (n/n); C: the ratio of PC to LPC (n/n); D: ultrasonic time, K1, K2 and K3 are the mean response values of corresponding levels. R represents the extreme difference of each factor.