Results of the antibacterial assays (see Fig. 6) of different shapes of ZNPs, curcumin-loaded ZNPs and pure curcumin against pathogenic bacterial stains.
Antimicrobial activity (5 mg mL−1) (mean inhibition zone diameter ± standard error − mm) | ||||||||
---|---|---|---|---|---|---|---|---|
E. coli | S. epidermidis | S. aureus | B. cereus | |||||
Well dif. | Drop dif. | Well dif. | Drop dif. | Well dif. | Drop dif. | Well dif. | Drop dif. | |
SZNP | 6.2 ± 0.4 | 8.6 ± 0.5 | 14.1 ± 0.3 | 18.6 ± 0.5 | 13.1 ± 0.7 | 14.6 ± 0.6 | 13.2 ± 0.8 | 14.1 ± 1.0 |
SZNP–C | 8.4 ± 0.8 | 10.2 ± 0.3 | 19.1 ± 0.1 | 22.2 ± 0.3 | 15.4 ± 1.1 | 17.0 ± 0.4 | 17.4 ± 0.7 | 19.6 ± 1.5 |
LPZNP | 8.2 ± 0.2 | 8.5 ± 0.6 | 15.7 ± 1.2 | 16.0 ± 0.7 | 13.1 ± 0.4 | 13.4 ± 0.7 | 13.0 ± 0.5 | 14.6 ± 0.2 |
LPZNP–C | 9.8 ± 0.3 | 10.0 ± 0.4 | 20.1 ± 0.2 | 20.8 ± 0.4 | 17.0 ± 0.5 | 16.8 ± 0.2 | 14.2 ± 0.5 | 17.8 ± 0.4 |
RZNP | 8.4 ± 0.1 | 9.7 ± 0.2 | 14.4 ± 0.4 | 17.4 ± 0.2 | 12.5 ± 0.3 | 14.3 ± 0.6 | 15.4 ± 0.8 | 18.9 ± 0.5 |
RZNP–C | 10.1 ± 0.5 | 10.7 ± 0.4 | 17.2 ± 0.4 | 20.0 ± 0.8 | 16.6 ± 0.7 | 17.7 ± 0.1 | 18.7 ± 0.2 | 20.2 ± 0.6 |
SPZNP | 7.8 ± 0.6 | 8.2 ± 0.4 | 14.1 ± 1.1 | 14.3 ± 0.1 | 13.0 ± 0.6 | 13.1 ± 0.7 | 11.4 ± 0.6 | 11.3 ± 0.1 |
SPZNP–C | 8.1 ± 0.1 | 8.9 ± 1.2 | 16.4 ± 0.4 | 17.7 ± 0.2 | 15.2 ± 0.8 | 15.9 ± 0.4 | 14.2 ± 0.4 | 13.5 ± 0.6 |
JZNP | 9.0 ± 0.5 | 10.3 ± 0.7 | 16.0 ± 0.6 | 16.7 ± 0.5 | 12.4 ± 0.1 | 15.0 ± 0.8 | 15.3 ± 0.4 | 16.0 ± 0.5 |
JZNP–C | 11.1 ± 0.2 | 10.5 ± 0.6 | 19.4 ± 0.1 | 20.9 ± 0.8 | 13.4 ± 0.4 | 15.5 ± 0.8 | 18.7 ± 0.3 | 19.3 ± 0.2 |
Curcumin (C) | 7.4 ± 1.3 | 7.8 ± 0.4 | 8.2 ± 0.3 | 9.0 ± 0.3 | 8.1 ± 0.4 | 8.8 ± 0.2 | 8.4 ± 1.1 | 7.9 ± 0.3 |
+ve control | 11.3 ± 0.8 | 14.1 ± 1.0 | 24.0 ± 0.4 | 28.1 ± 1.1 | 18.8 ± 1.1 | 22.1 ± 1.7 | 21.2 ± 2.0 | 24.0 ± 0.9 |
−ve control | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |