In silico ADMET properties of curcuminoids.
| Compound name | Solubility | BBB | CPY2D6 | Hepatotoxic | HIA | Alog p_98 | PSA |
|---|---|---|---|---|---|---|---|
| Keto-curcumin | 3 | 3 | NI | NT | 0 | 3.554 | 94.092 |
| Dihydrocurcumin | 3 | 3 | NI | NT | 0 | 3.577 | 94.092 |
| Octahydrocurcumin | 3 | 4 | NI | NT | 0 | 3.427 | 101.12 |
| Tetrahydrocurcumin | 3 | 3 | NI | NT | 0 | 3.6 | 94.092 |
| Alpha-turmerone | 2 | 0 | NI | NT | 0 | 4.079 | 17.3 |
| Beta-turmerone | 2 | 0 | NI | NT | 0 | 4.133 | 17.3 |
| Bisdemethoxycurcumin | 3 | 2 | NI | NT | 0 | 3.587 | 76.232 |
| Hexahydrocurcumin | 3 | 3 | NI | NT | 0 | 3.5 | 97.607 |
| Demethoxycurcumin | 3 | 2 | NI | NT | 0 | 3.57 | 85.162 |
| Cyclocurcumin | 3 | 2 | NI | NT | 0 | 3.213 | 85.722 |
| Curcumin glucuronide | 3 | 4 | NI | NT | 3 | 1.752 | 191.7 |
| Enol-curcumin | 3 | 4 | NI | NT | 0 | 3.573 | 97.607 |
| Ar-turmerone | 2 | 0 | NI | NT | 0 | 4.335 | 17.3 |
| Hexahydroxycurcuminol | 3 | 4 | NI | NT | 0 | 3.427 | 101.12 |