Drug-likeness property of curcuminoids.
| Compound name | PubChem CID | Lipinski's rule of 5 | Veber's rule | ||||
|---|---|---|---|---|---|---|---|
| HBD | HBA | MW | Alog P | RB | PSA | ||
| Keto-curcumin | 969516 | 6 | 2 | 368.38 | 3.554 | 8 | 93.06 |
| Dihydrocurcumin | 10429233 | 6 | 2 | 370.396 | 3.577 | 9 | 93.06 |
| Octahydrocurcumin | 11068834 | 6 | 4 | 376.443 | 3.427 | 10 | 99.38 |
| Tetrahydrocurcumin | 124072 | 6 | 2 | 372.412 | 3.6 | 10 | 93.06 |
| Alpha-turmerone | 14632996 | 1 | 0 | 218.335 | 4.079 | 4 | 17.07 |
| Beta-turmerone | 196216 | 1 | 0 | 218.335 | 4.133 | 4 | 17.07 |
| Bisdemethoxycurcumin | 5315472 | 4 | 2 | 308.328 | 3.587 | 6 | 74.6 |
| Hexahydrocurcumin | 5318039 | 6 | 3 | 374.428 | 3.5 | 10 | 96.22 |
| Demethoxycurcumin | 5469424 | 5 | 2 | 338.354 | 3.57 | 7 | 83.83 |
| Cyclocurcumin | 69879809 | 6 | 2 | 368.38 | 3.213 | 5 | 85.22 |
| Curcumin glucuronide | 71315012 | 12 | 5 | 544.504 | 1.752 | 11 | 189.28 |
| Enol-curcumin | 381330244 | 6 | 3 | 368.38 | 3.573 | 7 | 96.22 |
| Ar-turmerone | 558221 | 1 | 0 | 216.319 | 4.335 | 4 | 17.07 |
| Hexahydroxycurcuminol | Sketched | 6 | 4 | 376.443 | 3.427 | 10 | 99.38 |