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. 2020 Aug 27;10(52):31662–31669. doi: 10.1039/d0ra05374k

The effect of the amount of ionic liquid on the reaction.

Entrya Ratio Time (h) Yieldb (%)
1 0.01 2 80
2 0.05 2 85
3 0.1 2 93
4 0.2 2 93
5 1.0 2 93
6 0.1 4 98
7c 0.1 7 87
8d 0.1 4 90
a

Reaction conditions: xanthen-9-ol (0.5 mmol), indoles (0.5 mmol), 50 °C.

b

Isolated yields.

c

The reaction under room temperature.

d

The reaction at 40 °C.