The effect of the amount of ionic liquid on the reaction.
| Entrya | Ratio | Time (h) | Yieldb (%) |
|---|---|---|---|
| 1 | 0.01 | 2 | 80 |
| 2 | 0.05 | 2 | 85 |
| 3 | 0.1 | 2 | 93 |
| 4 | 0.2 | 2 | 93 |
| 5 | 1.0 | 2 | 93 |
| 6 | 0.1 | 4 | 98 |
| 7c | 0.1 | 7 | 87 |
| 8d | 0.1 | 4 | 90 |
Reaction conditions: xanthen-9-ol (0.5 mmol), indoles (0.5 mmol), 50 °C.
Isolated yields.
The reaction under room temperature.
The reaction at 40 °C.