Fig. 3.

Incidence rates of selected disease outcomes among patients with SSc or SSc-ILD (prevalence cohort): JMDC and MDV databases. Incidence rates for ILD in patients with SSc-ILD are not shown as all the patients in this group were diagnosed with ILD. Death: disenrolment from the insurance system with a cause categorized as “death” in JMDC and I46.1, I46.9, R96, R98, R99 or discharge summary (FF1 data) in MDV. Other selected disease outcomes were defined by ICD10 MHLW2013. ILD: J84.x; Heart failure: I50.x; Digital ulcer/gangrene: L98.x; Pulmonary hypertension: I27.x; Arrhythmia: I44.x, I45.x, I47.x, I48.x, I49.x; Respiratory failure: J96.x; Kidney failure: N17.x, N18.x, N19.x; Scleroderma renal crisis: M34.8; Pseudo-ileus: K56.x; Pericarditis: I30.x, I31.x, I32.x; Cardiomyopathy: I42.x, I43.x. ICD International Classification of Disease, ILD interstitial lung disease, IR incidence rate, PY patient years, SSc systemic sclerosis, SSc-ILD SSc-associated ILD