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. 2022 Mar 14;39(5):2065–2084. doi: 10.1007/s12325-022-02098-1

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 2 — Patients achieving no exacerbations, no OCS, ACQ-6, or FEV₁ ≥ 100 mL improvements a in SIROCCO/CALIMA after 6 months and 12 months or b in ZONDA after 6 months^a. ACQ-6 Asthma Control Questionnaire, 6-item, FEV₁ forced expiratory volume in 1 s, OCS oral corticosteroids, Q8W every 8 weeks. ^aN includes all patients still in the study at visit closest to timepoint. 6 months = week 24 (SIROCCO, CALIMA) or week 28 (ZONDA); 12 months = week 48 (SIROCCO) or week 56 (CALIMA)