Table 1.
Clinical characteristics and endometriosis-related symptoms.
| Adenomyosis (A) N = 77 | No adenomyosis (noA) N = 80 | p value | |
|---|---|---|---|
| Age, years (mean ± SD) | 38.22 ± 6.63 | 37.64 ± 5.85 | NS |
| BMI kg/m2 (mean ± SD) | 24.45 ± 4.98 | 23.90 ± 5.41 | NS |
| Parity (mean ± SD) | 0.43 ± 0.81 | 0.41 ± 0.83 | NS |
| Infertility** | 36 (46.75) | 28 (35) | NS |
| Hormonal treatment n (%) | |||
| None | 14 (18.18) | 13 (16.25) | NS |
| Combined contraceptives | 32 (41.55) | 36 (45) | |
| Progestins | 13 (16.88) | 13 (16.25) | |
| LNG-IUD | 5 (6.49) | 3 (3.75) | |
| aGnRH | 13 (16.88) | 15 (18.75) | |
| DE location n (%) | |||
| Torus uterinus | 49 (63) | 27 (33.75) | NS |
| Vaginal fornix | 16 (20.77) | 10 (12.50) | |
| Uterosacral ligaments | 44 (57.14) | 32 (40) | |
| Rectovaginal septum | 5 (6.49) | 6 (7.50) | |
| Ureteral + bladder | 14 (18.18) | 12 (15) | |
| Bowel | 35 (45.45) | 32 (40) | |
| Ovarian endometrioma n(%) | 60 (77.9) | 52 (65) | |
| Maximum size of DE nodules (mean ± SD) | |||
| Torus uterinus | 14.35 ± 6.09 | 13.77 ± 5.87 | NS |
| Vaginal fornix | 11.24 ± 5.68 | 12.05 ± 6.12 | |
| Uterosacral ligaments | 12.76 ± 4.77 | 11.55 ± 4.32 | |
| Rectovaginal septum | 21.14 ± 7.90 | 19.23 ± 6.78 | |
| Ureteral + bladder | 22.32 ± 6.41 | 23.12 ± 7.30 | |
| Bowel | 33.81 ± 9.72 | 34.92 ± 8.98 | |
| Uterine corpus size (mean ± SD) | |||
| Length | 69.91 ± 8.42 | 69.54 ± 7.20 | NS |
| Anteroposterior | 35.11 ± 5.45 | 34.33 ± 6.12 | |
| Transverse | 46.20 ± 12.31 | 43.92 ± 9.82 | |
| Previous endometriosis surgery n (%) | |||
| None | 33 (42.85) | 41 (51.25) | NS |
| 1 procedure | 34 (44.15) | 33 (41.25) | |
| ≥ 2 procedures | 10 (12.98) | 6 (7.50) | |
| AUB n (%) | |||
| No | 48 (62.33) | 51 (63.75) | NS |
| Yes | 29 (37.66) | 29 (36.25) | |
| Dysmenorrhea* (mean ± SD) | 7.20 ± 3.13 | 6.85 ± 3.03 | NS |
| Dyspareunia (mean ± SD) | 4.72 ± 4.05 | 4.61 ± 3.84 | NS |
| Dyschezia (mean ± SD) | 3.60 ± 3.87 | 3.88 ± 3.88 | NS |
| Non-cyclic pelvic pain (mean ± SD) | 4.69 ± 3.50 | 4.09 ± 3.49 | NS |
| Dysuria (mean ± SD) | 1.22 ± 2.81 | 1.02 ± 2.41 | NS |
Data are given as n or %. Symptoms are expressed with Numeric Rating Scale (NRS). LNG-IUD Levonorgestrel Intra Uterine Device, aGnRH analog-Gonadotropin-releasing Hormone, SD standard deviation, n number, % percentage, AUB Abnormal Uterine Bleeding, NS non-significant, BMI body mass index.
*Dysmenorrhea NRS was reported in patients with regular monthly periods: 14 patients in the A group (18.18%) and 13 in the noA Group (16.25%).
**Infertility: was defined as the failure to achieve pregnancy after 12 months without investigations or treatment.