In vitro anti-plasmodial activities of the oxygenated 3-alkylpyridine marine alkaloid analogues.

Compounds	IC50 (μM) ± SD	LC50 (μM) ± SD	SI
172	4.33 ± 0.87	45.52 ± 2.71	10.51
173	17.96 ± 3.59	98.43 ± 3.77	5.48
174	6.24 ± 0.31	67.54 ± 1.92	10.82
175	8.50 ± 0.14	105.12 ± 5.73	12.36
176	43.04 ± 4.30	120.00 ± 8.15	2.78
177	<3.38	52.67 ± 2.25	>15.58
178	<4.76	46.78 ± 4.65	>9.82
Chloroquine	0.625 ± 0.003	>100	>160