Synthesis of 1,4-disubstituted 1,2,3-triazoles catalyzed by Fe₃O₄@NFC-ImSalophCu^a.

Entry	Product	R	R1	Time (min)	Yieldb (%)	Mp (°C)		TON	Ref.
						Found	Reported
1	11a	Ph	Ph	30	97	169–170	169–171	485	46
2	11b	4-NO2	Ph	45	90	185–186	184–186	450	46
3	11c	4-Br	Ph	45	95	168–169	169–170	475	49
4	11d	Ph	CH2OH	45	90	115–116	115–117	475	47
5	11e	4-NO2	CH2OH	60	95	143–144	143–145	485	49
6	11f	4-Br	CH2OH	60	85	157–158	157–159	425	45
7	11g	Ph	MeCH–OH	30	94	128–129	127–129	470	49
8	11h	Ph	Me2C–OH	45	87	97–98	96–98	435	48
9	11i	4-NO2	Me2C–OH	90	95	127–128	126–128	475	49
10	11j	4-Br	Me2C–OH	60	75	169–171	170–171	375	47

^aReaction conditions: acetophenone (1.0 mmol), alkyne (1.0 mmol), sodium azide (1.2 mmol), catalyst (0.2 mol%) sodium ascorbate (2.5 mol%) and H₂O (3 ml), 65 °C.

^bIsolated yield.