In vitro activity of flavonoids of Consolida plants on promastigotes of Leishmania species.

R1–R5 (name, no.)	IC50 (μM)
	L. peruviana	L. braziliensis	J774.2 cells
R1 = R2 = R3 = R4 = R5 = H (kaempferol,132)	71.29	53.65	53.67
R1 = R2 = R3 = R4 = Ac, R4 = H (kaempferol tetraacetate, 132a)	53.32	68.56	15.56
R1 = R2 = R3 = R5 = H, R4 = OH (quercetin, 133)	60.04	30.49	125.44
R1 = R2 = R3 = R5 = Ac, R4 = OAc (quercetin pentaacetate, 133a)	11.18	46.78	109.23
R1 = β-d-Gal, R2 = R3 = R4 = R5 = H (trifolin, 134)	53.34	52.46	161.32
R1 = β-d-Gal Ac, R2 = R3 = R5 = H, R4 = H (trifolin heptaacetate, 134a)	10.53	8.72	148.71
R1 = 2-O-acetyl-β-d-Gal, R2 = R3 = R5 = H, R4 = OH (2′′-acetylhyperoside, 136)	7.35	6.21	122.31
R1 = 6-O-acetyl-β-d-Gal, R2 = R3 = R5 = H, R4 = OH (6′′-acetylhyperoside, 137)	86.95	51.60	61.32
Pentostam	11.32	9.56	12.44
Glucatim	15.33	25.61	15.20