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. Author manuscript; available in PMC: 2023 Apr 19.
Published in final edited form as: Circulation. 2022 Feb 4;145(16):1218–1233. doi: 10.1161/CIRCULATIONAHA.121.056850

Figure 2. lncExACT1 overexpression induces pathological hypertrophy.

Figure 2.

A. QRT-PCR measurement of lncExACT1 in mouse hearts 16 weeks after injection with AAV-lncExACT1 (lncExACT1) or AAV-GFP (Con). B Heart weight (HW) relative to tibial length (TL). C. Relative wall thickness (RWT). D. Fractional shortening (FS). E. Lung weight (LW) relative to tibial length (TL). F. Left ventricular end diastolic internal dimension (LVIDd). G. QRT-PCR measurement of hypertrophy markers in the heart. H. Quantification of cardiomyocyte area from wheat germ agglutinin (WGA)-stained heart sections. I. Quantification of EdU, PCM1 double-positive cardiomyocytes in heart sections. *p<0.05, **p<0.01 by Student’s t test. Data shown as mean±SEM.