The glide XP docking scores (in kcal mol−1) for the title compounds 1 and 2 and control inhibitor.
| Compound | Glide XP docking score | |
|---|---|---|
| DHFR | ||
| H. sapiens | S. aureus | |
| 1 | −6.5 | −6.9 |
| 2 | −5.4 | −7.5 |
| Trimethoprim (control inhibitor) | −6.0 | −7.3 |
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