Effect of nanocarriers on body weight and tumor volume in control and experimental ratsa.
| Body weight | Group I | Group II | Group III | Group IV |
|---|---|---|---|---|
| Initial | 199.5 ± 8.26 | 197.8 ± 2.99 | 198.6 ± 5.39 | 195.6 ± 5.81 |
| Final | 239.5 ± 4.33 | 210.1 ± 3.98* | 212.7 ± 4.85* | 243.2 ± 9.21 |
| Tumor volume (mm2) | — | 4502 ± 380* | 4289 ± 403* | 2954 ± 335 |
a
Group I, control; group II, cancer induced; group III, SLN unloaded treated; group IV, SLN loaded treated. Each value is expressed as the mean ± SD for six rats in each group. Significance as compared to group I shown as *P < 0.05.