Cytotoxic activities of compounds 1–11 (half maximal inhibitory concentration, IC50 in μM).
Comp. | BGC-823 | SMMC-7721 | Ichikawa | 7860 |
---|---|---|---|---|
1 | 33.1 | 25.7 | 24.8 | 28.3 |
2 | 42.6 | 52.1 | 16.5 | 24.7 |
3 | >100 | >100 | >100 | >100 |
4 | >100 | >100 | >100 | >100 |
5 | >100 | >100 | >100 | >100 |
6 | 34.6 | 26.5 | 23.6 | 26.1 |
7 | 46.2 | 56.5 | 17.8 | 23.5 |
8 | >100 | >100 | >100 | >100 |
9 | >100 | >100 | >100 | >100 |
10 | >100 | >100 | >100 | >100 |
11 | >100 | >100 | >100 | >100 |
Adriamycin | 1.48 | 2.24 | 1.2 | 2.0 |