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. 2022 Apr 28;10:e13353. doi: 10.7717/peerj.13353

Table 2. Analysis of genotypes and alleles in the IFNL4, MxA, and MxB genes between HBV infected persons and controls.

SNP HBV patients
(N = 448)
Controls
(N = 448)
P-value OR (95% CI)
rs11322783 (IFNL4)
Genotype
ΔG 1 1 0.479 1.000 [0.053–19.04]
ΔG/T 40 25 0.071 1.659 [1.000–2.812]
TT 407 422 0.075 0.612 [0.368–1.000]
Allele
ΔG 42 27 0.086 1.583 [0.970–2.566]
T 854 869 0.632 [0.390–1.031]
rs117648444 (IFNL4)
Genotype
AA 0 0
AG 11 7 0.475 1.586 [0.627–4.119]
GG 437 441 0.475 0.631 [0.243–1.595]
Allele
A 11 7 0.477 1.579 [0.630–4.115]
G 885 889 0.634 [0.243–1.588]
rs2071430 (MxA)
Genotype
GG 230 217 0.423 1.123 [0.867–1.456]
GT 168 188 0.195 0.830 [0.632–1.087]
TT 50 43 0.511 1.183 [0.767–1.801]
Allele
G 628 622 0.797 1.032 [0.844–1.262]
T 268 274 0.969 [0.792–1.185]
rs17000900 (MxA)
Genotype
AA 12 13 0.999 0.921 [0.414–1.988]
AC 112 114 0.939 0.977 [0.726–1.314]
CC 324 321 0.882 1.034 [0.775–1.380]
Allele
A 136 140 0.844 0.966 [0.746–1.250]
C 760 756 1.035 [0.800–1.340]
rs9982944 (MxB)
Genotype
AA 37 40 0.812 0.918 [0.576–1.452]
AG 204 222 0.255 0.851 [0.656–1.103]
GG 207 186 0.178 1.210 [0.930–1.576]
Allele
A 278 302 0.246 0.885 [0.725–1.079]
G 618 594 1.130 [0.926–1.380]
rs408825 (MxB)
Genotype
CC 19 18 0.999 1.058 [0.560–2.024]
CT 126 131 0.768 0.947 [0.712–1.260]
TT 303 299 0.831 1.041 [0.784–1.370]
Allele
C 164 167 0.903 0.978 [0.771–1.240]
T 732 729 1.022 [0.806–1.297]
rs2838029 (MxB)
Genotype
AA 1 5 0.219 0.198 [0.017–1.434]
AG 60 58 0.921 1.040 [0.702–1.544]
GG 387 385 0.923 1.038 [0.712–1.516]
Allele
A 62 68 0.649 0.905 [0.635–1.284]
G 834 828 1.105 [0.779–1.576]