LacNAc-containing N-glycan peaks of salivary glycoproteins showed unique or decreased glycopatterns in patients with T2DM compared to HVs^a.

No	Calculated m/z	Ion type	Predicted components	Proposed N-glycan structureb	Relative intensities of N-glycans		Fold change (T2DM patients/HVs)
					HVs (%)	T2DM patients (%)
1	1705.561	H	Hex4HexNAc4S1dHex1		3.165	ND	0
2	2020.747	H	Hex5HexNAc3(α2,3)NeuAc1dHex2		2.259	ND	0
3	2121.795	H	Hex6HexNAc4(α2,6)NeuAc1		2.350	ND	0
4	1736.623	Na	Hex4HexNAc3dHex3		23.095	11.651	0.504
5	1793.644	Na	Hex4HexNAc4dHex2		30.949	14.696	0.475
6	1939.702	Na	Hex4HexNAc4dHex3		30.112	9.331	0.310

^a .

^bProposed glycan structure, monosaccharides are represented according to MS-tools from the GlycoWorkbench software.