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. 2022 Apr 6;11(4):214–225. doi: 10.1302/2046-3758.114.BJR-2021-0192.R1

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© 2022 Author(s) et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/

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Fig. 4 — The composition and diversity of gut microbiome in the exercised post-traumatic osteoarthritic (PTOA) animals. a) Linear discriminant analysis effect size (LEfSe) analysis of the fecal bacterial community of the sham/sedentary (Sed), PTOA/Sed, and PTOA/treadmill-walking (TW) groups. b) Comparison of the fecal microbial community diversity of the Sham/Sed, PTOA/Sed, and PTOA/TW group, including comparison of the number of observed operational taxonomic units, Chao 1 index, Shannon index, and Simpson index. c) Trajectory of the gut microbiome structure of rats based on Bray-Curtis distance. LDA, linear discriminant analysis.