Table II.
Mean percentage change in C-terminal telopeptide of type I collagen and N-terminal propeptide of type I procollagen value compared to baseline.
| Variable | Mean, μg/l (SD) | Mean percentage change from baseline (95% CI) | p-value* |
|---|---|---|---|
| CTX | |||
| Baseline | 0.42 (0.32) | N/A | N/A |
| 6 wks | 0.71 (0.44) | 64 (47 to 82) | < 0.001 |
| 12 wks | 0.55 (0.25) | 32 (18 to 48) | < 0.001 |
| P1NP | |||
| Baseline | 45.5 (26.1) | N/A | N/A |
| 6 wks | 154.0 (76.1) | 240 (206 to 278) | < 0.001 |
| 12 wks | 147.0 (64.9) | 217 (183 to 255) | < 0.001 |
p < 0.05 indicates statistical significance.
*
t-tests with Satterthwaite’s method.
CI, confidence interval; CTX, C-terminal telopeptide of type I collagen; N/A, not applicable; P1NP, N-terminal propeptide of type I procollagen; SD, standard deviation.