Figure 7. Deleting Tim-3 on DCs but not on CD8⁺ T cells impedes the trogocytosis of CD8⁺ TILs in vivo.

Representative flow cytometry dot plots and summary data (n = 5, left) showing frequencies of CD11c⁺, CD209⁺, and CD14⁺ PD-1⁺Tim-3⁺ CD8⁺ TILs in Havcr2^fl/fl, Havcr2^fl/fl Cd11c^cre, and Havcr2^fl/fl E8i^cre mice implanted with YUMMER 1.7 (day 21). Results shown are from 1 experiment (n = 5), representative of 2 independent experiments. P values were obtained from unpaired t tests. **P < 0.01; ***P < 0.001; ****P < 0.0001. Data indicate mean ± SD.