Figure 4. Offspring of SG-operated mice remain smaller than offspring of sham-operated mice until weaning.
(A and B) Weight and fasting blood glucose at P21 of male and female offspring of sham- and SG-operated mice. (C and D) Fasting level of insulin and glucagonat P21 in offspring of sham- and SG-operated mice. (E) Fractions of α, β, and δ cells in the pancreata of P21 mice. Blue: offspring of sham-operated mice, red: offspring of SG-operated mice. **P < 0.01 by 2-way ANOVA with Tukey HSD post hoc test in A and B; by 2-tailed Student’s t test in C and D; and by χ2 test in E. In A and B, sham-operated male mice n = 23, sham-operated female mice n = 16, SG-operated male mice n = 26, SG-operated female mice n = 25; in C, sham-operated mice n = 38, SG-operated mice n = 38; in D, sham-operated mice n = 40, SG-operated mice n = 46; and in E, cumulative of pancreata of 10 mice each from sham- and SG-operated mice.