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. 2022 Apr 8;7(7):e153488. doi: 10.1172/jci.insight.153488

Figure 8. Knockdown of KLF5 results in decreased proliferation in vitro and in vivo.

Figure 8

(A) Cell cycling analysis histogram charts for ModFit. Quantifications on the chart represent the percentage of cells in the S-phase (n = 3). (B) Quantification of percentage cells in S-phase after ModFit curve fitting (n = 3). (C) Immunofluorescence (IF) staining of EdU and Ki67 in C2BBECtrl and C2BBEΔIND cells treated with DMSO/DOX and PBS/IL-22. (D) Quantification of percentage of cells in S-phase from IF images (n = 3). (E) IF staining of EdU in CO- or TAM-treated Klf5Ctrl or Klf5ΔIND mice. Data from graphs represent mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001; 1-way ANOVA. Scale bars: 70 μm.