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. 2022 Apr 1;14(4):e23742. doi: 10.7759/cureus.23742

Table 1. Summary of reported cases of RCC metastasis to thyroid gland tumors, including the type of recipient tumor, interval from nephrectomy, other sites of metastases, and IHC profile of metastatic RCC.

IHC, immunohistochemistry; FA, follicular adenoma; FVPTC, follicular variant of papillary thyroid carcinoma; M, months; PTC, papillary thyroid carcinoma; RCC, renal cell carcinoma; TG, thyroglobulin; Y, years

# Author Recipient Tumor Interval Other Metastasis IHC of Metastatic RCC
1 Rosai (cited by Ryška and Čáp [7]) FA NA NA TG (-)
2 Baloch and LiVolsi [8] FVPTC 2Y Liver, pancreas TG, CK19 (-)
3 Wolf et al. [9] FA 2Y NA NA
4 Ryška and Čáp [7] Hurthle cell (oncocytic) carcinoma 13M Subcutaneous AE1/AE3, vimentin, EMA (+); TG, CEA, CK19, calcitonin (-)
5 Qian et al. [10] Hurthle cell Adenoma synchronous None Vimentin, CD10 (+); TG, TTF-1 (-)
6 Koo et al. [3] FA 5Y None CK, CD10, galectin-3 (equivocal); TG, TTF-1, calcitonin (-)
7 Bohn et al. [11] PTC 2Y Spinal vertebrae RCC (+); TG (-)
8 Yu et al. [12] FVPTC 3Y None CAM 5.2, CD10, vimentin (+); TG, TTF-1, RCC (-)
9 Medas et al. [2] FA 6Y None CD10 (+); TG, TTF-1, galectin-3 (-)
10 Kefeli and Mete [4] FVPTC 18Y None PAX-8, CD10 (+); vimentin (equivocal); TG, TTF-1, CEA, calcitonin (-)
11 Current case FVPTC 14Y Contralateral kidney PAX-8, CAIX, galectin-3, vimentin (+); TG, TTF-1, CK7, CK19 (-)