Table 1. Summary of reported cases of RCC metastasis to thyroid gland tumors, including the type of recipient tumor, interval from nephrectomy, other sites of metastases, and IHC profile of metastatic RCC.
IHC, immunohistochemistry; FA, follicular adenoma; FVPTC, follicular variant of papillary thyroid carcinoma; M, months; PTC, papillary thyroid carcinoma; RCC, renal cell carcinoma; TG, thyroglobulin; Y, years
# | Author | Recipient Tumor | Interval | Other Metastasis | IHC of Metastatic RCC |
1 | Rosai (cited by Ryška and Čáp [7]) | FA | NA | NA | TG (-) |
2 | Baloch and LiVolsi [8] | FVPTC | 2Y | Liver, pancreas | TG, CK19 (-) |
3 | Wolf et al. [9] | FA | 2Y | NA | NA |
4 | Ryška and Čáp [7] | Hurthle cell (oncocytic) carcinoma | 13M | Subcutaneous | AE1/AE3, vimentin, EMA (+); TG, CEA, CK19, calcitonin (-) |
5 | Qian et al. [10] | Hurthle cell Adenoma | synchronous | None | Vimentin, CD10 (+); TG, TTF-1 (-) |
6 | Koo et al. [3] | FA | 5Y | None | CK, CD10, galectin-3 (equivocal); TG, TTF-1, calcitonin (-) |
7 | Bohn et al. [11] | PTC | 2Y | Spinal vertebrae | RCC (+); TG (-) |
8 | Yu et al. [12] | FVPTC | 3Y | None | CAM 5.2, CD10, vimentin (+); TG, TTF-1, RCC (-) |
9 | Medas et al. [2] | FA | 6Y | None | CD10 (+); TG, TTF-1, galectin-3 (-) |
10 | Kefeli and Mete [4] | FVPTC | 18Y | None | PAX-8, CD10 (+); vimentin (equivocal); TG, TTF-1, CEA, calcitonin (-) |
11 | Current case | FVPTC | 14Y | Contralateral kidney | PAX-8, CAIX, galectin-3, vimentin (+); TG, TTF-1, CK7, CK19 (-) |