Fig. 2.

Results of light transmission aggregometry in various inherited platelet disorders. (A, B) Normal aggregation patterns to various platelet agonists. (C) Results in Bernard-Soulier syndrome. Note that absence of aggregation to ristocetin, but normal to others. (D) Results in Glanzmann thrombasthenia. Absent aggregation with all agonists except ristocetin. (E) and (F) Results in platelet-type von Willebrand disease. Normal aggregation to all agonists and aggregation also was observed even at low concentrations of ristocetin, which does not occur in normal specimens (adapted from [32]).