Skip to main content
. 2022 Apr 13;28(7-8):312–329. doi: 10.1089/ten.tea.2021.0137

FIG. 7.

FIG. 7.

Lower stiffness hydrogels support modest vascularization 24 weeks post-VML. (A–E) Representative images of vascular staining at 24 weeks post-VML. Images were taken in the zone of regeneration showing αSMA structures (green, arrow) and CD31 cells (red, arrowhead) at the defect-tissue interface. (F) Quantification of αSMA structures indicative of arteries and veins was significantly reduced across all experimental groups compared to native muscle. (G) Lower stiffness hydrogels (1 and 3 kPa) supported statistically similar levels of CD31+ cells to native muscle. Data presented as mean ± SD. *p < 0.05, **p < 0.01. n = 3 muscles per experimental group. Scale bar: 100 μm. αSMA, α-smooth muscle actin. Color images are available online.