Table 1.
Convalescent HCWs N = 26 |
Uninfected HCWs N = 35 |
|
---|---|---|
Age (years) | 54 (41–61) | 52 (41–57) |
Sex (Female n, %) | 16 (62%) | 24 (69%) |
Body Mass Index (Kg/m2) | 24 (22.4–27) | 23.4 (21.3–25.4] |
Comorbidities (n, %) Hypertension Diabetes |
3 (11%) 1 (4%) |
4 (11%) 2 (6%) |
Working at COVID ward Time working at COVID ward, weeks History of (n, %): Positive SARS-CoV-2 RT-PCR |
15 (58%) 6 (4–9) 21 (81%) |
20 (57%) 10 (4–12) - |
Positive anti-N SARS-CoV-2 IgG | 16 (61%) | – |
Time from | ||
Inclusion to vaccination (days) | 153 (138–161) | 145 (127–155) |
Infection to vaccination (days) | 327 (319–335) | |
Pre-vaccine: | ||
Positive IgG N-specific antibodies Median value (RU/mL) |
12 (46%) 10,1 (4.8–24.2) |
0 4,75 (3,7–6,2) |
CD8 + T cell response to S (n, %) CD4 + T cell response to S (n, %) |
12 (46%) 11 (42%) |
9 (26%) 7 (20%) |
Values are expressed as median, interquartile range unless otherwise explained; HCW, health care workers; RT-PCR, real time polymerase chain reaction; RU, relative units.