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. 2020 Nov 24;10(69):42457–42492. doi: 10.1039/d0ra07204d

Fmoc-removal with alternative bases to piperidine reported by Lebl and co-workers65.

Base (25% in DMF) t 1/2 a (min)
Piperidine 2.0
2-Me-piperidine 3.0
3-Me-piperidine 1.9
4-Me-piperidine 2.0
4-Me-piperazine 7.8
a

Fmoc-Ile CTC-resin was placed in a glass cuvette and the deprotection mixture was added. The UV absorbance at 301 nm was determined every 2 min.