Comparison of piperidine and 4-Me-piperidine in the synthesis of four 10-mer peptides65.
Peptide name/sequencea | Purity (RP-HPLC, %) | |
---|---|---|
Piperidine | 4-Me-piperidine | |
(Enkephalin)2 (YGGFLYGGFL) | 92.3 | 92.5 |
LHRH (EHWSYGWLPG) | 91.7 | 91.2 |
ACP (65–74) (VQAAIDYING) | 83.6 | 84.0 |
β-Amyloid (25–34) (GSNKGAIIGL) | 93.6 | 93.5 |
No detailed description of the synthesis was provided by the authors.