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. 2020 Nov 24;10(69):42457–42492. doi: 10.1039/d0ra07204d

Comparison of piperidine and 4-Me-piperidine in the synthesis of four 10-mer peptides65.

Peptide name/sequencea Purity (RP-HPLC, %)
Piperidine 4-Me-piperidine
(Enkephalin)2 (YGGFLYGGFL) 92.3 92.5
LHRH (EHWSYGWLPG) 91.7 91.2
ACP (65–74) (VQAAIDYING) 83.6 84.0
β-Amyloid (25–34) (GSNKGAIIGL) 93.6 93.5
a

No detailed description of the synthesis was provided by the authors.