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. 2022 Apr 18;9:864188. doi: 10.3389/fcvm.2022.864188

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Copyright © 2022 Cui, Ye, Wang, Yang, Zhu, Hu, Lan, Huang, Wang, Gu, Yan, Ma, Qi and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MCELNs inhibited the apoptosis of H9C2 cells after radiation exposure. Western blot images (A) and quantitation (B) of apoptotic proteins cleaved-caspase3 and cleaved-PARP in H9C2 cells after 48 h of culture with indicated treatment. Annexin V apoptosis Flow detection (C) and quantitation (D) of the apoptosis rate in H9C2 cells after 48 h of culture with indicated treatment. IR (–/+): 0/16 Gy X-ray; MCELNs (–/+): 0/10 μg/mL. All data were represented as means ± SD (n = 3 independent experiments). The statistical significance was evaluated by one-way ANOVA followed by the Turkey's multiple comparisons test among groups.