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. 2022 Apr 29;5(9):e202101337. doi: 10.26508/lsa.202101337

Figure S11. Maturation of converted versus unconverted DC in TdLN after radiation therapy and intratumoral pIC.

Figure S11.

MC38 tumors were established in Kaede mice. When tumors reached 5–6 mm average diameter, they were photoconverted with violet light and treated with 12-Gy radiation in combination 50 μg intratumoral poly I:C or left untreated. The TdLN was harvested 3 d after treatment to assess the expression of the maturation marker CD80 on unconverted or converted DC. (A) Representative histograms of CD80 expression on (i) mig CD11b+ DC or (ii) mig CD103+ DC left untreated or treated with RT+pIC. (A, B) Summary of CD80 expression on DC populations as in (A). *P < 0.05, ***P < 0.001 and ****P < 0.0001.