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. 2022 Apr 22;19(4):259–267. doi: 10.30773/pi.2021.0316

Table 2.

Z-scores of neurocognitive performances in chronic insomniacs compared among insomniacs using benzodiazepine group, drug-free insomniacs, and controls

Insomniacs using benzodiazepine (a)
Drug-free insomniacs (b)
Controls (c)
F p Post hoc
N=29 N=27 N=28
Global cognition
Mini-Mental State Examination -0.18±1.01 0.45±0.75 0.24±1.00 2.73 0.072
Attention/concentration
Digit span backward 0.16±1.30 0.61±1.25 0.51±1.13 2.68 0.075
Memory
Word list recognition -0.14±0.89 0.07±0.7 0.12±0.68 0.18 0.833
Word list recall -0.07±0.92 0.29±1.04 0.47±1.02 0.82 0.447
Recall of constructional praxis 0.08±1.03 0.28±0.81 0.35±1.06 1.67 0.195
Executive function
Trail making test digit symbol test A 0.73±0.66 1.27±0.38 1.09±0.47 10.2 <0.001 a<b, a<c
Categorical fluency -0.01±0.99 1.26±0.97 0.77±1.08 4.32 0.002 a<b
Frontal assessment battery 0.28±0.70 0.56±0.69 0.25±0.80 2.34 0.104
Constructional praxis 0.20±0.65 0.36±0.43 0.25±0.69 0.23 0.796
Visuospatial abilities
Clock drawing 0.08±0.85 0.28±0.50 0.33±0.52 1.60 0.209

Data are presented as mean±standard deviation. Multivariable analysis of covariance after adjusting for confounders (including Epworth sleepiness scale and Beck Depression Inventory, and exposure of other psychotropics) and Bonferroni’s correction for multiple comparisons (p<0.005=0.05/10) were conducted