Parameter values of biphasic model. ‘θb’ is the contribution of initial burst release over total mass drug release, ‘kb’ is the initial burst constant, ‘kd’ is the diffusion kinetic constant, ‘n’ is the diffusion exponent, dt represents the time shift.
| θ b | k b | k d | n | dt | |
|---|---|---|---|---|---|
| Valsartan | 0.69 | 0.045 | 4.65 × 10−4 | 1.012 | 118.7 |
| EC-valsartan | 0.75 | 0.029 | 3.01 × 10−4 | 1.011 | 117.3 |
| PMMA-valsartan | 0.64 | 0.017 | 1.56 × 10−4 | 1.011 | 116.4 |