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. 2022 Apr 29;15:17562848221092594. doi: 10.1177/17562848221092594

Table 1.

Characteristics of studies included in meta-analysis.

Study (year) Study design Country N Endoscope technology Activity scores Endoscopy versus histology
WLE Advanced Endoscopic Histological Correlation coefficient Accuracy assessed a
Fluxá et al. 15 Prospective Chile 91 SD MES Geboes Spearman’s
Frieri et al. 16 Prospective Italy 52 SD MES Gupta Spearman’s
Irani et al. 17 Prospective UK 125 SD UCEIS NI, RHI Spearman’s
Lemmens et al. 18 Retrospective Belgium 263 NA b MES Geboes Kendall’s
Lobatón et al. 19 Prospective Belgium 96 HD MES Geboes Spearman’s
Osterman et al. 20 Prospective USA 101 HD MES Total Riley Spearman’s
Rosenberg et al. 21 Prospective USA 103 HD MES Geboes Spearman’s
Simsek et al. 22 Retrospective Turkey 109 NA b EAI HSS Kendall’s Yes
Kim et al. 23 Retrospective Korea 82 HD MES Geboes Spearman’s
Iacucci et al. 24 Retrospective Canada 78 i-SCAN i-SCAN NYMS Spearman’s
Iacucci et al. 25 Retrospective Multicentre 160 HD i-SCAN MES, PICaSSO RHI Kendall’s Yes
Iacucci et al. 26 Prospective Canada 41 HD i-SCAN MES, i-SCAN-OE RHI Spearman’s Yes
Iacucci et al. 27 Prospective Canada 82 HD i-SCAN MES, PICaSSO RHI c Yes
Iacucci et al. 28 Prospective Multicentre 302 HD i-SCAN MES, PICaSSO RHI Pearson’s Yes
Honzawa et al. 29 Retrospective Japan 15 HD i-SCAN MES Geboes Kendall’s
Trivedi et al. 30 Retrospective Multicentre 72 HD i-SCAN PICaSSO NYMS Spearman’s
Kanmura et al. 31 Prospective Japan 73 HD LCI MES Geboes Spearman’s Yes

EAI, Rachmilewitz endoscopic activity index; HD, high definition; HSS, Harpaz histopathological activity scoring system; MES, Mayo Endoscopic Score; NI, Nancy Index; NYMS, New York Mount Sinai Score; PICaSSO, Paddington International virtual ChromoendoScopy ScOre; RHI, Robarts Histopathology Index; SD, standard definition; UCEIS, Ulcerative Colitis Endoscopic Index of Severity; WLE, White light endoscopy.

a

Indicates those studies that assessed the predictive accuracy of a dichotomized endoscopic activity score to predict the presence of activity on histology.

b

The study stated that WLE was used, but it was unclear whether this was SD or HD.

c

The study was designed specifically to assess the ability of endoscopy to identify patients in clinical remission, and so they did not report a correlation coefficient.