Table 1.
Characteristics of studies included in meta-analysis.
| Study (year) | Study design | Country | N | Endoscope technology | Activity scores | Endoscopy versus histology | |||
|---|---|---|---|---|---|---|---|---|---|
| WLE | Advanced | Endoscopic | Histological | Correlation coefficient | Accuracy assessed a | ||||
| Fluxá et al. 15 | Prospective | Chile | 91 | SD | – | MES | Geboes | Spearman’s | – |
| Frieri et al. 16 | Prospective | Italy | 52 | SD | – | MES | Gupta | Spearman’s | – |
| Irani et al. 17 | Prospective | UK | 125 | SD | – | UCEIS | NI, RHI | Spearman’s | – |
| Lemmens et al. 18 | Retrospective | Belgium | 263 | NA b | – | MES | Geboes | Kendall’s | – |
| Lobatón et al. 19 | Prospective | Belgium | 96 | HD | – | MES | Geboes | Spearman’s | – |
| Osterman et al. 20 | Prospective | USA | 101 | HD | – | MES | Total Riley | Spearman’s | – |
| Rosenberg et al. 21 | Prospective | USA | 103 | HD | – | MES | Geboes | Spearman’s | – |
| Simsek et al. 22 | Retrospective | Turkey | 109 | NA b | – | EAI | HSS | Kendall’s | Yes |
| Kim et al. 23 | Retrospective | Korea | 82 | HD | – | MES | Geboes | Spearman’s | – |
| Iacucci et al. 24 | Retrospective | Canada | 78 | – | i-SCAN | i-SCAN | NYMS | Spearman’s | – |
| Iacucci et al. 25 | Retrospective | Multicentre | 160 | HD | i-SCAN | MES, PICaSSO | RHI | Kendall’s | Yes |
| Iacucci et al. 26 | Prospective | Canada | 41 | HD | i-SCAN | MES, i-SCAN-OE | RHI | Spearman’s | Yes |
| Iacucci et al. 27 | Prospective | Canada | 82 | HD | i-SCAN | MES, PICaSSO | RHI | – c | Yes |
| Iacucci et al. 28 | Prospective | Multicentre | 302 | HD | i-SCAN | MES, PICaSSO | RHI | Pearson’s | Yes |
| Honzawa et al. 29 | Retrospective | Japan | 15 | HD | i-SCAN | MES | Geboes | Kendall’s | – |
| Trivedi et al. 30 | Retrospective | Multicentre | 72 | HD | i-SCAN | PICaSSO | NYMS | Spearman’s | – |
| Kanmura et al. 31 | Prospective | Japan | 73 | HD | LCI | MES | Geboes | Spearman’s | Yes |
EAI, Rachmilewitz endoscopic activity index; HD, high definition; HSS, Harpaz histopathological activity scoring system; MES, Mayo Endoscopic Score; NI, Nancy Index; NYMS, New York Mount Sinai Score; PICaSSO, Paddington International virtual ChromoendoScopy ScOre; RHI, Robarts Histopathology Index; SD, standard definition; UCEIS, Ulcerative Colitis Endoscopic Index of Severity; WLE, White light endoscopy.
Indicates those studies that assessed the predictive accuracy of a dichotomized endoscopic activity score to predict the presence of activity on histology.
The study stated that WLE was used, but it was unclear whether this was SD or HD.
The study was designed specifically to assess the ability of endoscopy to identify patients in clinical remission, and so they did not report a correlation coefficient.