Table 2.
All-cause unadjusted healthcare resource utilization for CDI patients with and without sepsis: 12-months postindex follow-up.
| Died | Survived | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary CDI only | Any recurrent CDI a | Primary CDI only | Any recurrent CDI a | |||||||||
| No sepsis | Sepsis | p value | No sepsis | Sepsis | p value | No sepsis | Sepsis | p value | No sepsis | Sepsis | p value | |
| N = 74,804 | N = 84,093 | N = 20,332 | N = 33,526 | N = 135,636 | N = 51,360 | N = 62,829 | N = 34,909 | |||||
| Length of follow-up (days),b mean (SD) | 66.1 (91.0) | 60.5 (91.8) | <0.0001 | 121.0 (92.6) | 116.8 (91.5) | <0.0001 | 353.9 (51.4) | 346.8 (64.9) | <0.0001 | 356.5 (43.6) | 351.9 (52.5) | <0.0001 |
| Median | 22.0 | 12.0 | <0.0001 | 88.0 | 84.0 | <0.0001 | 365 | 365 | <0.0001 | 365 | 365 | <0.0001 |
| Time from index CDI to first recurrence (days), mean (SD) | NA | NA | 31.6 (15.3) | 33.5 (15.6) | <0.0001 | NA | NA | 33.3 (20.1) | 35.0 (20.2) | <0.0001 | ||
| Median | NA | NA | 27.0 | 30.0 | <0.0001 | NA | NA | 28.0 | 30.0 | <0.0001 | ||
| Inpatient hospitalization (%) | 91.2 | 95.7 | <0.0001 | 92.2 | 99.2 | <0.0001 | 81.6 | 97.9 | <0.0001 | 82.8 | 99.0 | <0.0001 |
| ICU stay (%) | 15.1 | 29.1 | <0.0001 | 33.8 | 65.0 | <0.0001 | 14.9 | 38.0 | <0.0001 | 19.1 | 49.2 | <0.0001 |
| Inpatient average LOS (days) – mean (SD) | 10.2 (10.3) | 12.1 (13.5) | <0.0001 | 8.8 (7.4) | 11.6 (11.5) | <0.0001 | 6.9 (6.5) | 9.1 (9.1) | <0.0001 | 6.6 (5.7) | 9.0 (7.7) | <0.0001 |
ICU, intensive care unit; LOS, length of stay; NA, not applicable; SD, standard deviation.
a
Any recurrent CDI during follow-up of up to 12 months.
b
Mean follow-up time for those who survived is <365 days due to patients who disenrolled for reasons other than death.