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Binding of imipenem and faropenem to PBPs of P. aeruginosa PAO1
| PBP | Panem concn (μg/ml) required to inhibit the binding of [14C]benzylpenicillin by 50%
|
|
|---|---|---|
| Faropenem | Imipenem | |
| 1b | 0.23 | 0.13 |
| 1c | 0.15 | 0.15 |
| 2 | 0.19 | 0.13 |
| 3 | 0.20 | 0.18 |
| 4 | 0.13 | 0.61 |
| 5/6 | >1 | 0.16 |
