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. 2021 Jul 3;46(2):255–265. doi: 10.1016/j.jgr.2021.06.011

Fig. 3.

Fig. 3

Rb1 significantly promoted mitophagy and upregulated AMPKα phosphorylation in AMI-injured mice. The expression of (A) FUNDC1, (B) PINK1, (C) Parkin, (D) LC3Ⅱ/LC3Ⅰ and (E) p62 were detected using western blot analysis. (F) The expression of PINK1, Parkin and LC3 were detected using immunohistochemistry (400 × ). Scale bar = 50 μm. (G) The expression of p-AMPKα and AMPKα were detected using western blot analysis. All the experiments were performed in triplicate. Results were presented as mean ± SD. #P < 0.05, ##P < 0.01 vs. the sham group; ∗P < 0.05, ∗∗P < 0.01 vs. the model group.