Skip to main content
. 2022 Apr 23;79:104002. doi: 10.1016/j.ebiom.2022.104002

Figure 4.

Fig 4

Mediation analyses between the childhood traumatic events, the mental health problems and cognitive measures with a mean strength of functional connectivity links which were significantly correlated with the childhood traumatic events as a mediator. Path a: relationship between childhood traumatic events and functional connectivity links; Path b: the relationship between functional connectivity links and mental health problems/cognitive measures; Path c: the relationship between childhood traumatic events and mental health problems/cognitive measures; Path a*b represents an indirect path which is the relationship between childhood traumatic events and mental health problems/cognitive measures that is mediated by the mean strength of the functional connectivity links which were significantly correlated with the childhood traumatic events. Path a*b indicates the extent to which taking the functional connectivity strength into account can explain the effect of the childhood traumtic events on mental health and cognitive measures inlcuding: addiction (1.9% of the variance explained), anxiety (1.3% of the variance explained), depression (1.0% of the variance explained), mental distress (0.8% of the variance explained), self-harm (0.5% of the variance explained), well-being (1.4% of the variance explained), fluid intelligence (3.0% of the variance explained), and prospective memory (3.3% of the variance explained).