Table 1.
Patient Characteristics. The values in the Healed and Not Healed Column indicates the mean value of the data points. The P-value was determined by Student’s unpaired t-test with unequal variance.
| Feature Name | Healed (n = 164) | Not Healed (n = 44) | P-value |
|---|---|---|---|
| Wound length | 0.788 | 0.823 | 0.817 |
| Wound width | 1.063 | 1.712 | 0.004 |
| Wound depth | 0.306 | 0.434 | 0.053 |
| Foot | 0.556 | 0.666 | 0.129 |
| Age | 60.458 | 58.594 | 0.387 |
| Gender | 0.347 | 0.219 | 0.052 |
| Ethnicity_Hispanic | 0.007 | 0.016 | 0.613 |
| CCI | 7.139 | 6.438 | 0.216 |
| DR | 0.174 | 0.234 | 0.330 |
| ALC | 1.69E+09 | 1.71E+09 | 0.822 |
| HbA1c | 8.370 | 8.569 | 0.537 |
| Albumin | 3.971 | 3.890 | 0.180 |
| Pre-Albumin | 22.534 | 25.698 | 0.010 |
| CKD Stage | 0.713 | 1.171 | 0.022 |
| CRP | 3.081 | 3.984 | 0.205 |
| ESR | 41.873 | 51.001 | 0.047 |
| Infection | 0.288 | 0.516 | 0.002 |
| PTB | 0.039 | 0.208 | 0.001 |
| X-ray | 0.102 | 0.150 | 0.296 |
| MRI | 0.083 | 0.219 | 0.020 |
| tc99 | 0.007 | 0.031 | 0.294 |
| DP_measured | 0.850 | 0.830 | 0.690 |
| PT_measured | 0.837 | 0.808 | 0.579 |
| AnkSys_measured | 0.104 | 0.266 | 0.010 |
| ToeSys_measured | 0.125 | 0.266 | 0.026 |
| TcPO2 | 0.000 | 0.063 | 0.045 |
| BSA | 2.843 | 3.398 | 0.491 |
| BMI | 35.175 | 33.909 | 0.297 |
| TCC | 0.033 | 0.005 | 0.058 |
| Offload | 0.395 | 0.352 | 0.513 |
| Immunosuppressants | 0.049 | 0.078 | 0.443 |
| Oral Steroids | 0.368 | 0.250 | 0.084 |
| Antihypertensives | 0.722 | 0.828 | 0.082 |
| Oral Hypoglycemics | 0.431 | 0.375 | 0.453 |
| Canagliflozin | 0.014 | 0.000 | 0.158 |
| Insulin | 0.694 | 0.750 | 0.407 |
| Heparin | 0.056 | 0.094 | 0.359 |
| Allopurinol | 0.076 | 0.063 | 0.713 |
| NSAIDs | 0.563 | 0.594 | 0.676 |
| ASA | 0.528 | 0.531 | 0.963 |
| Coumadin | 0.146 | 0.078 | 0.133 |
| Xa inhibitors | 0.000 | 0.000 | Undefined |
| Race_African | 0.111 | 0.234 | 0.041 |
| Race_Asian | 0.007 | 0.047 | 0.151 |
| Race_Caucasian | 0.875 | 0.703 | 0.008 |
| Race_Other | 0.007 | 0.016 | 0.613 |
| UTSA Stage | 1.155 | 1.274 | 0.069 |
| ischemia | 0.343 | 0.316 | 0.545 |
CCI: Charlson comorbidity index. DR: Diabetic retinopathy. ALC: Absolute lymphocyte count. CKD: Chronic Kidney Disease. CRP: C-reactive protein. ESR: Erythrocyte sedimentation rate. PTB: Probe to bone test. Tc99: Technetium 99 bone scan. DP: Dorsalis pedis pulse. PT: Posterior tibial pulse. TcPO2: Transcutaneous oxygen pressure. BSA: Body surface area. BMI: Body mass index. TCC: Total contact cast use. NSAID: Nonsteroidal anti-inflammatory drug. ASA: Aspirin.