Table 1.
Studies reporting SARS-CoV-2 RNA testing of plasma samples from asymptomatic/presymptomatic blood donors
| Country | Donors tested, n | Donors positive, n (%) | Comments | Reference |
|---|---|---|---|---|
| China (Wuhan) | 7,425 | 4 (0.05) | Testing in MPs of 6–8 samples; RT-PCR results showed low signal strength suggesting low levels of RNA; infectious virus not confirmed; samples collected on January 2020 | [83] |
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| China (Hubei) | 94,342 | 0 | 96.1% of samples tested in MP of 8 and 3.9% tested as ID; samples collected on February–April 2020 | [82] |
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| Pakistan | 600 | 2 (0.33) | Not indicated if ID or MP testing; samples collected on March–April 2020 | [84] |
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| Brazil | 4,103 | 1 (0.02) | Testing in MPs of 4; low viral load; 27 donors had detectable RNA in saliva samples, 8 with high viral load; samples collected on June–September 2020 | [86] |
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| USA | 258,000 samples tested in 17,995 MPs | 3 (0.001) | Testing in MPs of 6 or 16; low viral loads (<103−<4 × 104 copies/mL); infectious virus not detected; samples collected on March–September 2020 | [85] |
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| ||||
| Italy | 1,797 | 0 | Not indicated if ID or MP testing; 10 of 1,797 donors were SARS-CoV-2 antibody positive and tested for RNA; 0 of 10 were positive; samples collected on March–June 2020 | [87] |
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| Portugal | 543 | 0 | Not indicated if ID or MP testing; 7 donor samples were SARS-CoV-2 IgM positive; samples collected on June-July 2020 | [88] |
RT-PCR, reverse transcriptase polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; MP, minipool; ID, individual donation.