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. 2022 Apr 15;65(8):6088–6099. doi: 10.1021/acs.jmedchem.1c01984

Table 1. Curating Compounds Based on Activity against S. aureus vs E. coli.

pathogen compound 1 compound 2   compound 1887
S. aureus pMIC ≥ 5 pMIC ≥ 5 ... pMIC ≥ 5
E. coli pMIC ≥ 5 pMIC < 5 pMIC ≥ 5
final labela 1 0   1
a

Compounds that are active against both pathogens above a threshold MIC are labeled “1” (GN-permeable), and compounds that are active against S. aureus but inactive against E. coli are labeled “0” (GN-impermeable).