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. 2022 Apr 20;65(8):6338–6351. doi: 10.1021/acs.jmedchem.2c00368

Table 6. Potency of 22 and 23 in the Inhibition of the Hydrolysis of Different LPC Species.

LPC 22 IC50 (μM) 22 residual activity (%) 23 IC50 (μM) 23 residual activity (%)
14:0 0.084 1 0.054 0
16:0 0.072 12 0.034 12
18:1 0.045 5 0.029 7
20:0 0.032 49 0.033 51